European Journal of Clinical Microbiology & Infectious Diseases

, Volume 31, Issue 4, pp 389–395

Human Angiostrongylus cantonensis: an update

Authors

  • Q.-P. Wang
    • Center for Parasitic Organisms, State Key Laboratory of Biocontrol, School of Life SciencesSun Yat-Sen University
  • Z.-D. Wu
    • Key Laboratory of Tropical Diseases and Control of the Ministry of Education, Zhongshan Medical SchoolSun Yat-Sen University
  • J. Wei
    • Key Laboratory of Tropical Diseases and Control of the Ministry of Education, Zhongshan Medical SchoolSun Yat-Sen University
  • R. L. Owen
    • Departments of Medicine, Epidemiology and BiostatisticsUniversity of California
    • Center for Parasitic Organisms, State Key Laboratory of Biocontrol, School of Life SciencesSun Yat-Sen University
    • Key Laboratory of Tropical Diseases and Control of the Ministry of Education, Zhongshan Medical SchoolSun Yat-Sen University
Review

DOI: 10.1007/s10096-011-1328-5

Cite this article as:
Wang, Q., Wu, Z., Wei, J. et al. Eur J Clin Microbiol Infect Dis (2012) 31: 389. doi:10.1007/s10096-011-1328-5

Abstract

Angiostrongylus cantonensis was first discovered in 1935 and has become an important emerging pathogen causing human angiostrongyliasis. Major outbreaks of human angiostrongyliasis have been reported in endemic regions. Thousands of cases of human angiostrongyliasis have been documented worldwide. A. cantonensis has spread from its traditional endemic regions of the Pacific islands and Southeast Asia to the American continent including the USA, Caribbean islands and Brazil. Humans acquire A. cantonensis by consumption of raw or undercooked intermediate snail hosts or paratenic hosts. The main clinical manifestations of human angiostrongyliasis are eosinophilic meningitis and ocular angiostrongyliasis. The treatment of this disease includes supportive treatment, corticosteroid therapy, and combined therapy with corticosteroids and anthelminthics. The most effective method for prevention is to persuade people not to eat raw or undercooked intermediate and paratenic hosts.

Copyright information

© Springer-Verlag 2011