Persistence of Streptococcus pneumoniae urinary antigen excretion after pneumococcal pneumonia

  • F. Andreo
  • C. Prat
  • J. Ruiz-Manzano
  • L. Lores
  • S. Blanco
  • M. A. Cuesta
  • M. Giménez
  • J. Domínguez
Concise Article

DOI: 10.1007/s10096-008-0606-3

Cite this article as:
Andreo, F., Prat, C., Ruiz-Manzano, J. et al. Eur J Clin Microbiol Infect Dis (2009) 28: 197. doi:10.1007/s10096-008-0606-3

Abstract

The aim of this study was to determine the duration of Streptoccocus pneumoniae antigen excretion in urine after pneumococcal pneumonia. Urinary antigen detection remained positive in nonconcentrated urine in 18 (52.9%) of the 34 patients in the first month after pneumonia diagnosis. In 12 of these positive cases, the test was still positive in the second month, in six patients after 4 months, and in two cases 6 months after the diagnosis of pneumonia. Using concentrated urine, antigenuria remained positive in all patients for at least 3 months, with antigen detected in three cases more than one year later. We did not observe a relation between age, gender, immunosuppression, underlying diseases, pneumonia severity, positive blood culture, or X-ray presentation and longer-term antigenuria excretion. However, the small number of patients evaluated is a limitation for statistical analysis. In order to correctly analyse a positive urinary antigen test result in patients with pneumonia, it is necessary to know which patients have recently had a previous episode of pneumonia.

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • F. Andreo
    • 2
  • C. Prat
    • 1
  • J. Ruiz-Manzano
    • 2
  • L. Lores
    • 3
  • S. Blanco
    • 1
  • M. A. Cuesta
    • 1
  • M. Giménez
    • 1
  • J. Domínguez
    • 1
    • 4
  1. 1.Servei de Microbiologia, Hospital Universitari Germans Trias i PujolFundació Institut d’Investigació en Ciències de la Salut Germans Trias I Pujol, Universitat Autònoma de Barcelona, CIBER Enfermedades RespiratoriasBadalonaSpain
  2. 2.Servei de Pneumologia, Hospital Universitari Germans Trias i PujolFundació Institut d’Investigació en Ciències de la Salut Germans Trias I Pujol, Universitat Autònoma de Barcelona, CIBER Enfermedades RespiratoriasBadalonaSpain
  3. 3.Servei de PneumologiaHospital de Sant BoiBarcelonaSpain
  4. 4.Servei de MicrobiologiaFundació Institut d’Investigació en Ciències de la Salut Germans Trias I PujolBarcelonaSpain