Panton-Valentine leukocidin genes and staphylococcal chromosomal cassette mec types amongst Finnish community-acquired methicillin-resistant Staphylococcus aureus strains, 1997–1999

  • M. Kardén-Lilja
  • S. Ibrahem
  • J. Vuopio-Varkila
  • S. Salmenlinna
  • O. Lyytikäinen
  • L. Siira
  • A. Virolainen
Concise Article

DOI: 10.1007/s10096-007-0334-0

Cite this article as:
Kardén-Lilja, M., Ibrahem, S., Vuopio-Varkila, J. et al. Eur J Clin Microbiol Infect Dis (2007) 26: 729. doi:10.1007/s10096-007-0334-0

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) strains from Finland covering years 1997–1999 were studied for the presence of Panton-Valentine leukocidin (PVL) gene loci, and the clinically well-defined community-acquired MRSA (CA-MRSA) strains (n = 108) also for staphylococcal chromosomal cassette mec (SCCmec) and multilocus sequence types (MLST). Only a minority (12%) of the CA-MRSA strains contained the PVL gene loci and possessed genotypes formerly described as typical to CA-MRSA strains. The majority of these strains were heterogenous by MLST and pulsed-field gel electrophoresis (PFGE) analysis but, however, harboured the SCCmec cassette type IV. In conclusion, it seems doubtful to consider only molecular characteristics such as the presence of PVL genes as definite markers for CA-MRSA strains.

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  • M. Kardén-Lilja
    • 1
  • S. Ibrahem
    • 1
  • J. Vuopio-Varkila
    • 1
  • S. Salmenlinna
    • 1
    • 2
  • O. Lyytikäinen
    • 3
  • L. Siira
    • 1
  • A. Virolainen
    • 1
  1. 1.Department of Bacterial and Inflammatory DiseasesNational Public Health InstituteHelsinkiFinland
  2. 2.Haartman Institute, Department of Bacteriology and ImmunologyUniversity of HelsinkiHelsinkiFinland
  3. 3.Department of Infectious Disease EpidemiologyNational Public Health InstituteHelsinkiFinland

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