Concise Article

European Journal of Clinical Microbiology and Infectious Diseases

, Volume 21, Issue 4, pp 304-306

First online:

Tula Virus Infection Associated with Fever and Exanthema After a Wild Rodent Bite

  • D. SchultzeAffiliated withDepartment of Virology, Institute for Clinical Microbiology and Immunology, Frohbergstrasse 3, 9001 St. Gallen
  • , Å. LundkvistAffiliated withSwedish Institute for Infectious Disease Control, Karolinska Institutet, Stockholm, S-17182 Solna
  • , U. BlauensteinAffiliated withUniversity Childrens Hospital Basel, Clinic of Neuropediatry, PO Box, 4005 Basel
  • , P. HeymanAffiliated withResearch Laboratory for Vector-Borne Diseases and National Reference Center for Hantavirus Infections, Queen Astrid Military Hospital, Bruynstraat 2, 1120 Brussels

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Reported here is the first case of human acute infection with Tula virus, which occurred in a 12-year-old boy in Switzerland. This hantavirus had been considered apathogenic to humans, and in Switzerland only TULV-genome sequences have been demonstrated in wild rodents to date. In this case, paronychia, fever and exanthema occurred after the patient was bitten by a wild rodent, indicating an unusual route of hantavirus transmission. Thus, Tula virus infection should be taken into account in patients with appropriate clinical symptoms and contact with rodents.