Neurological Sciences

, Volume 21, Supplement 1, pp S71–S73

MRI in neuronal ceroid lipofuscinosis

  • L. D'Incerti

DOI: 10.1007/s100720070043

Cite this article as:
D'Incerti, L. Neurol Sci (2000) 21: S71. doi:10.1007/s100720070043


Magnetic resonance imaging in neuronal ceroid lipofuscinosis (NCL) demonstrates cerebral and cerebellar atrophy, T2-hyperintensity of the lobar white matter and thinning of the cerebral cortex. The association of these findings, although non specific, can be observed in all the different forms of NCL, narrows the differential diagnosis of the infantile progressive encephalopathies and may suggest the diagnosis.

Key words Magnetic resonance imagingProgressive encephalopathyBrain atrophyWhite matterCerebral cortexBasal ganglia

Copyright information

© Springer-Verlag Italia 2000

Authors and Affiliations

  • L. D'Incerti
    • 1
  1. 1.Department of Neuroradiology, National Neurological Institute C. Besta, Via Celoria 11, I-20133 Milan, ItalyIT