Neurological Sciences

, Volume 32, Issue 2, pp 313–315

Nocturnal frontal lobe epilepsy presenting with restless leg syndrome-like symptoms

  • Irene Aricò
  • Rosaria Condurso
  • Francesca Granata
  • Lino Nobili
  • Oliviero Bruni
  • Rosalia Silvestri
Case Report

DOI: 10.1007/s10072-010-0448-5

Cite this article as:
Aricò, I., Condurso, R., Granata, F. et al. Neurol Sci (2011) 32: 313. doi:10.1007/s10072-010-0448-5

Abstract

We describe the case of a 22-year-old male affected by NFLE reporting paroxysmal RLS-like symptoms. The patient was referred to our Sleep Center due to nocturnal paresthesias and cramps involving the left leg and leading to sleep fragmentation. At age 4, the patient presented with secondary generalized seizures preceded by left leg discomfort, controlled on CBZ. After successive therapy discontinuation, leg symptoms built up in frequency and duration until a secondary generalized seizure re-occurred. On CBZ prompt resumption no further GM seizures occurred albeit persistence of night-time frequent cramps and paraesthesia. Sleep EEG demonstrated asymmetric interictal sharp theta on the right posterior frontal areas, whereas brain MRI results were consistent with a Taylor type right frontal cortical dysplasia. CBZ augmentation and add on therapy with LEV led to further frequency reduction of sensory symptoms.

Keywords

NFLE RLS Cortical dysplasia Taylor-type 

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Irene Aricò
    • 1
  • Rosaria Condurso
    • 1
  • Francesca Granata
    • 2
  • Lino Nobili
    • 3
  • Oliviero Bruni
    • 4
  • Rosalia Silvestri
    • 1
  1. 1.Department of Neurosciences, Sleep Medicine CenterMessina Medical SchoolMessinaItaly
  2. 2.Department of Radiological SciencesUniversity of MessinaMessinaItaly
  3. 3.Centre of Epilepsy Surgery “C. Munari”, Center of Sleep MedicineNiguarda HospitalMilanItaly
  4. 4.Department of Developmental Neurology and PsychiatryCenter for Pediatric Sleep DisordersRomeItaly

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