Neurological Sciences

, Volume 29, Supplement 3, pp 296–300

Aging

Authors

  • Samantha Galluzzi
    • LENITEM — Laboratory of Epidemiology, Neuroimaging and TelemedicineIRCCS Centro San Giovanni di Dio Fatebenefratelli
  • Alberto Beltramello
    • Neuroradiology ServiceOspedale Maggiore
  • Massimo Filippi
    • Neuroimaging Research Unit, Department of NeurologyScientific Institute and University, Ospedale San Raffaele
    • LENITEM — Laboratory of Epidemiology, Neuroimaging and TelemedicineIRCCS Centro San Giovanni di Dio Fatebenefratelli
    • Psychogeriatric WardIRCCS Centro San Giovanni di Dio Fatebenefratelli
Article

DOI: 10.1007/s10072-008-1002-6

Cite this article as:
Galluzzi, S., Beltramello, A., Filippi, M. et al. Neurol Sci (2008) 29: 296. doi:10.1007/s10072-008-1002-6

Abstract

The normal adult brain undergoes considerable morphological changes with aging. Studying these changes is paramount to differentiate normal age-related brain variations from the effects of neurodegenerative diseases affecting brain structure in the elderly. Considerable progress has been made in this research area during the past few decades, given the availability of noninvasive imaging tools such as magnetic resonance (MR). In recent years image acquisition devices, computer technology and software development have also advanced, allowing sophisticated methods for analyzing brain images, at both the macro-and microstructural level. In this article we will review studies assessing the effect of aging on global and regional gray and white matter volume using advanced MR techniques.

Keywords

Magnetic resonanceAgingGray matterWhite matterAdvanced imaging

Copyright information

© Springer-Verlag Italia 2008