Neurological Sciences

, 29:290

Basic concepts of advanced MRI techniques

  • Elisabetta Pagani
  • Alberto Bizzi
  • Francesco Di Salle
  • Nicola De Stefano
  • Massimo Filippi
Article

DOI: 10.1007/s10072-008-1001-7

Cite this article as:
Pagani, E., Bizzi, A., Di Salle, F. et al. Neurol Sci (2008) 29(Suppl 3): 290. doi:10.1007/s10072-008-1001-7

Abstract

An overview is given of magnetic resonance (MR) techniques sensitized to diffusion, flow, magnetization transfer effect, and local field inhomogeneities induced by physiological changes, that can be viewed, in the clinical practice, as advanced because of their challenging implementation and interpretation. These techniques are known as diffusion-weighted, perfusion, magnetization transfer, functional MRI and MR spectroscopy. An important issue is that they can provide quantitative estimates of structural and functional characteristics that are below the voxel resolution. This review does not deal with the basic concepts of the MR physics and the description of the available acquisition and postprocessing methods, but hopefully provides an adequate background to readers and hence facilitate the understanding of the following clinical contributions.

Keywords

Magnetic resonance imagingDiffusionPerfusionMagnetization transferFunctional MRIProton MR spectroscopy

Copyright information

© Springer-Verlag Italia 2008

Authors and Affiliations

  • Elisabetta Pagani
    • 1
  • Alberto Bizzi
    • 2
  • Francesco Di Salle
    • 3
  • Nicola De Stefano
    • 4
  • Massimo Filippi
    • 1
  1. 1.Neuroimaging Research Unit, Department of NeurologyScientific Institute and University Ospedale San RaffaeleMilanItaly
  2. 2.Departments of Neuroradiology and Child NeurologyFondazione IRCCS Istituto Neurologico “Carlo Besta”MilanItaly
  3. 3.Department of NeurosciencesUniversity of PisaPisaItaly
  4. 4.Department of Neurological and Behavioural SciencesUniversity of SienaSienaItaly