Updates in Clinical Neurology

Neurological Sciences

, Volume 29, Issue 2, pp 238-240

Different types of fatigue in patients with facioscapulohumeral dystrophy, myotonic dystrophy and HMSN-I. Experienced fatigue and physiological fatigue

  • Joke S. KalkmanAffiliated withDepartment of Medical Psychology, Radboud University Nijmegen Medical CentreExpert Centre Chronic Fatigue, Radboud University Nijmegen Medical Centre
  • , Machiel J. ZwartsAffiliated withDepartment of Clinical Neurophysiology, Institute of Neurology, Radboud University Nijmegen Medical Centre Email author 
  • , Maartje L. SchillingsAffiliated withDepartment of Clinical Neurophysiology, Institute of Neurology, Radboud University Nijmegen Medical Centre
  • , Baziel G. M. van EngelenAffiliated withNeuromuscular Centre Nijmegen, Institute of Neurology, Radboud University Nijmegen Medical Centre
  • , Gijs BleijenbergAffiliated withExpert Centre Chronic Fatigue, Radboud University Nijmegen Medical Centre

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

Although fatigue is a common symptom in neuromuscular disorders, little is known about different types of fatigue. Sixty-five FSHD, 79 adult-onset MD and 73 HMSN type I patients were studied. Experienced fatigue was assessed with the CIS-fatigue subscale. Physiological fatigue was measured during a 2-min sustained maximal voluntary contraction of the biceps brachii muscle using the twitch interpolation technique to assess central activation failure (CAF) and peripheral fatigue. Experienced fatigue, CAF and peripheral fatigue appeared to be predominantly separate types of fatigue.

Keywords

Experienced fatigue Central activation failure Peripheral fatigue Neuromuscular disorders