Neurological Sciences

, Volume 28, Supplement 2, pp S150–S155

Migraine and epilepsy: clinical and pathophysiological relations

Authors

    • Headache Centre, Neurological Sciences DepartmentUniversity “Federico II” of Naples
  • A. Ranieri
    • Headache Centre, Neurological Sciences DepartmentUniversity “Federico II” of Naples
  • E. Marano
    • Headache Centre, Neurological Sciences DepartmentUniversity “Federico II” of Naples
  • L. Beneduce
    • Headache Centre, Neurological Sciences DepartmentUniversity “Federico II” of Naples
  • P. Ripa
    • Headache Centre, Neurological Sciences DepartmentUniversity “Federico II” of Naples
  • L. Bilo
    • Epilepsy Centre, Neurological Sciences DepartmentUniversity “Federico II” of Naples
  • R. Meo
    • Neurology Outpatients ServiceAzienda Sanitaria Locale 1
  • V. Bonavita
    • Istituto di Diagnosi e Cura Hermitage Capodimonte
COMORBILITY OF MIGRAINE

DOI: 10.1007/s10072-007-0769-1

Cite this article as:
De Simone, R., Ranieri, A., Marano, E. et al. Neurol Sci (2007) 28: S150. doi:10.1007/s10072-007-0769-1

Abstract

Migraine and epilepsy are both chronic disorders characterised by recurrent neurological attacks, with a partial clinical and therapeutic overlap and frequently occurring together. Although still incompletely clarified, the possible existence of a link between migraine and epilepsy has long been debated. In this paper the epidemiologic evidence of migraine and epilepsy comorbidity, the possible occurrence of both disturbances in close temporal association, possible shared physiopathologic mechanisms and the rationale for antiepileptic drug use in migraine prophylaxis will be discussed.

Key words

MigraineEpilepsyClinical relationsPathophysiological relationsReview
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© Springer-Verlag Italia 2007