Urticaria as a Presenting Manifestation of Adult-Onset Still’s Disease
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- Salaffi, F., Filosa, G., Bugatti, L. et al. Clin Rheumatol (2000) 19: 389. doi:10.1007/s100670070034
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Adult-onset Still’s disease (AOSD) is a rare disorder of unknown aetiology, characterised by high spiking fever, an evanescent, erythematous, maculopapular rash, arthralgia or arthritis, lymphadenopathy, hepatosplenomegaly, sore throat and serositis. It is associated with marked leukocytosis, high erythrocyte sedimentation rate, increased level of serum ferritin and negative rheumatoid factor and antinuclear antibody tests. Here we report a patient in whom an urticaria-like rash was an uncommon presenting clinical feature of AOSD. To our knowledge, this association has only been reported once before.