Clinical Rheumatology

, Volume 27, Issue 1, pp 107–110

Radiological aid to clinical diagnosis of Schnitzler’s syndrome: multimodality imaging approach

  • Alejandro Fernández Flórez
  • Elena Gallardo Agromayor
  • Rosario García-Barredo
  • Rosa Ma Landeras Alvaro
  • Miren Gorriño Angulo
  • Victor Manuel Martínez-Taboada
  • Ma Antonia Fernández Echevarría
Brief Report

DOI: 10.1007/s10067-007-0758-z

Cite this article as:
Flórez, A.F., Gallardo Agromayor, E., García-Barredo, R. et al. Clin Rheumatol (2008) 27: 107. doi:10.1007/s10067-007-0758-z

Abstract

Schnitzler’s syndrome is a rare combination of chronic urticaria, fever of unknown origin, disabling bone pain, and monoclonal gammopathy. We report a case with an unusual radiological manifestation as a solitary sclerotic lesion of the right iliac bone. Its main features on conventional radiography, computed tomography, and magnetic resonance imaging are described, and the main radiological differential diagnoses are discussed to help with the characterization of this syndrome, which requires a combination of clinical, laboratory, and radiological data. On the other hand, although our patient had an excellent clinical response to anakinra, the sclerotic lesion remained unchanged on follow-up X-ray examinations.

Keywords

Bone painChronic urticariaIliac boneMonoclonal gammopathySclerotic lesion

Copyright information

© Clinical Rheumatology 2007

Authors and Affiliations

  • Alejandro Fernández Flórez
    • 1
  • Elena Gallardo Agromayor
    • 1
  • Rosario García-Barredo
    • 1
  • Rosa Ma Landeras Alvaro
    • 1
  • Miren Gorriño Angulo
    • 2
  • Victor Manuel Martínez-Taboada
    • 3
  • Ma Antonia Fernández Echevarría
    • 1
  1. 1.Department of Diagnostic Radiology, Faculty of MedicineUniversity Hospital “Marqués de Valdecilla” (HUMV), University of CantabriaSantanderSpain
  2. 2.Department of Diagnostic RadiologyHospital of BasurtoBilbaoSpain
  3. 3.Department of Rheumatology, Faculty of MedicineHUMV, University of CantabriaSantanderSpain