Anti-topoisomerase I antibodies in systemic lupus erythematosus as a marker of severe nephritis
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- Hamidou, M.A., Audrain, M.A., Masseau, A. et al. Clin Rheumatol (2006) 25: 542. doi:10.1007/s10067-005-0061-9
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The authors report nine patients with systemic lupus erythematosus associated with anti-topoisomerase I antibodies (ELISA test) without features of systemic sclerosis. These antibodies were correlated with the disease activity and might be a marker of the severity of the closely related to difusse proliferative glomerulonephritis.