Clinical Rheumatology

, Volume 23, Issue 4, pp 355–357

A case of anti-Jo1 myositis with pleural effusions and pericardial tamponade developing after exposure to a fermented Kombucha beverage

Case Report

DOI: 10.1007/s10067-004-0890-y

Cite this article as:
Derk, C.T., Sandorfi, N. & Curtis, M.T. Clin Rheumatol (2004) 23: 355. doi:10.1007/s10067-004-0890-y


The pathogenesis of the idiopathic inflammatory myopathies has been postulated to be an environmental trigger causing the expression of the disease in a genetically predisposed patient. We report a case of anti-Jo1 antibody-positive myositis which was associated with pleural effusions, pericardial effusion with tamponade, and ‘mechanic’s hands’, probably related to the consumption of a fermented Kombucha beverage. Kombucha ‘mushroom’, a symbiosis of yeast and bacteria, is postulated to be the trigger for our patient’s disease owing to the proximity of his symptoms to the consumption of the Kombucha beverage.


Anti-Jo1AntisynthetaseKombucha Myositis



Alanine transferase


Aspartate aminotransferase


Creatinine phosphokinase

Copyright information

© Clinical Rheumatology 2004

Authors and Affiliations

  • Chris T. Derk
    • 1
  • Nora Sandorfi
    • 1
  • Mark T. Curtis
    • 2
  1. 1.Division of RheumatologyThomas Jefferson University HospitalPhiladelphiaUSA
  2. 2.Department of PathologyThomas Jefferson University HospitalPhiladelphiaUSA