Journal of Artificial Organs

, Volume 17, Issue 1, pp 16–22

Paracorporeal ventricular assist device as a bridge to transplant candidacy in the era of implantable continuous-flow ventricular assist device

  • Hideaki Suwa
  • Osamu Seguchi
  • Tomoyuki Fujita
  • Yoshihiro Murata
  • Michinari Hieda
  • Takuya Watanabe
  • Takuma Sato
  • Haruki Sunami
  • Masanobu Yanase
  • Hiroki Hata
  • Takeshi Nakatani
Original Article Artificial Heart (Clinical)

DOI: 10.1007/s10047-013-0731-3

Cite this article as:
Suwa, H., Seguchi, O., Fujita, T. et al. J Artif Organs (2014) 17: 16. doi:10.1007/s10047-013-0731-3

Abstract

Ventricular assist devices (VADs) have long been used as bridge to transplant therapy (BTT). Nipro-Toyobo paracorporeal pulsatile-flow VAD (nt-VAD) was the only device available until April 2011, when implantable continuous-flow VADs (cf-VADs) became available. Although cf-VADs are central to BTT, nt-VAD remains a necessary option. We aimed to clarify the role of nt-VAD in an era of increasing cf-VAD use. We retrospectively reviewed patients who underwent VAD implantation at the National Cerebral and Cardiovascular Center from May 2011 to March 2013. Characteristics were compared between the nt-VAD and cf-VAD groups. Twenty-nine patients (mean age 37.7 ± 11.1 years, 23 males) underwent VAD implantation. Fifteen patients initially received nt-VADs, although 4 were converted to cf-VADs. Of these 15 patients, 3 were too small for cf-VADs and 2 needed bilateral ventricular support. The remaining 10 patients received nt-VADs (7 patients at INTERMACS level 1 and 3 at level 2). The nt-VAD group patients had significantly more preoperative mechanical circulatory support and were in a more critical condition before VAD implantation than the cf-VAD group. The 2-year survival rate was not significantly different. Despite the critical conditions of nt-VAD patients, their overall survival is not statistically inferior to that of cf-VAD patients. nt-VAD is a good option as a BTC for the patient with urgent and critical condition.

Keywords

Ventricular assist deviceBridge to transplant candidacyImplantable continuous-flow ventricular assist deviceParacorporeal pulsatile-flow ventricular assist device

Copyright information

© The Japanese Society for Artificial Organs 2013

Authors and Affiliations

  • Hideaki Suwa
    • 1
  • Osamu Seguchi
    • 2
  • Tomoyuki Fujita
    • 3
  • Yoshihiro Murata
    • 2
  • Michinari Hieda
    • 2
  • Takuya Watanabe
    • 2
  • Takuma Sato
    • 2
  • Haruki Sunami
    • 2
  • Masanobu Yanase
    • 2
  • Hiroki Hata
    • 3
  • Takeshi Nakatani
    • 2
  1. 1.Department of Cardiovascular MedicineNational Cerebral and Cardiovascular CenterSuitaJapan
  2. 2.Department of TransplantationNational Cerebral and Cardiovascular CenterSuitaJapan
  3. 3.Department of Adult Cardiac SurgeryNational Cerebral and Cardiovascular CenterSuitaJapan