Optical Review

, 12:37

Proposition of Single Molecular Orientation Determination Using polarization Controlled Beam by Liquid Crystal Spatial Light Modulators


DOI: 10.1007/s10043-005-0037-7

Cite this article as:
Hashimoto, M., Yamada, K. & Araki, T. OPT REV (2005) 12: 37. doi:10.1007/s10043-005-0037-7


We have proposed a method to control the three-dimensional electric field in the focus of an optical microscope using two non-twisted liquid crystal spatial light modulators, and to detect the molecular orientation of a single molecule. The three-dimensional electric field is generated by focusing the beam with two dimensional spatial distribution of polarization. The possibility of detection of three-dimensional single molecular orientation was shown by numerical calculations. © 2005 The Optical Society of Japan

Key words

molecular orientation optical microscopy single molecular detection fluorescence microscopy liquid crystal spatial light modulator 

Copyright information

© The Optical Society of Japan 2005

Authors and Affiliations

  • Mamoru Hashimoto
    • 1
  • Kazuaki Yamada
    • 1
  • Tsutomu Araki
    • 1
  1. 1.Department of Mechanical Science and Bioengineering, Graduate School of Engineering ScienceOsaka UniversityToyonaka, OsakaJapan

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