ENVIRONMENTAL, BIOLOGICAL, AND SPACE

Optical Review

, Volume 10, Issue 2, pp 74-76

Temperature-Insensitive Measurement of Glucose Concentration Based on Near Infrared Spectroscopy and Partial Least Squares Analysis

  • Hidenobu ArimotoAffiliated withInstitute of Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology
  • , Masatoshi TarumiAffiliated withNikkiso Co., Ltd.
  • , Yukio YamadaAffiliated withInstitute of Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and TechnologyDepartment of Mechanical Engineering and Intelligent Systems, University of Electro-Communications

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Abstract

Temperature-insensitive partial least squares analysis for glucose measurement is presented based on Near Infrared spectroscopy in the wavelength range from 1,250 to 1,800nm. Experiments are performed using aqueous glucose solutions. To create a temperature-insensitive prediction model, the glucose concentration and water temperature are varied independently. The results of the predicted glucose concentration agree well with the actual glucose concentration with an error of 4.4%.

Key words

blood glucose measurement non-invasive measurement multivariate analysis PLS NIR spectroscopy