Journal of Human Genetics

, Volume 52, Issue 4, pp 308–316

Population history of the Dniester–Carpathians: evidence from Alu markers

  • Alexander Varzari
  • Wolfgang Stephan
  • Vadim Stepanov
  • Florina Raicu
  • Radu Cojocaru
  • Yuri Roschin
  • Cristiana Glavce
  • Valentin Dergachev
  • Maria Spiridonova
  • Horst D. Schmidt
  • Elisabeth Weiss
Original Article

DOI: 10.1007/s10038-007-0113-x

Cite this article as:
Varzari, A., Stephan, W., Stepanov, V. et al. J Hum Genet (2007) 52: 308. doi:10.1007/s10038-007-0113-x

Abstract

The area between the Dniester and the eastern Carpathian mountain range is at a geographical crossroads between eastern Europe and the Balkans. Little is known about the genetics of the population of this region. We performed an analysis of 12 binary autosomal markers in samples from six Dniester–Carpathian populations: two Moldavian, one Romanian, one Ukrainian and two Gagauz populations. The results were compared with gene frequency data from culturally and linguistically related populations from Southeast Europe and Central Asia. Small genetic differences were found among southeastern European populations (in particular those of the Dniester–Carpathian region). The observed homogeneity suggests either a very recent common ancestry of all southeastern European populations or strong gene flow between them. Despite this low level of differentiation, tree reconstruction and principle component analyses allowed a distinction between Balkan–Carpathian (Macedonians, Romanians, Moldavians, Ukrainians and Gagauzes) and eastern Mediterranean (Turks, Greeks and Albanians) population groups. The genetic affinities among Dniester–Carpathian and southeastern European populations do not reflect their linguistic relationships. The results indicate that the ethnic and genetic differentiations occurred in these regions to a considerable extent independently of each other. In particular, Gagauzes, a Turkic-speaking population, show closer affinities to their geographical neighbors than to other Turkic populations.

Keywords

Alu insertion DNA polymorphism Moldavians Romanians Ukrainians Gagauzes Population structure 

Copyright information

© The Japan Society of Human Genetics and Springer 2007

Authors and Affiliations

  • Alexander Varzari
    • 1
    • 2
    • 6
  • Wolfgang Stephan
    • 2
  • Vadim Stepanov
    • 7
  • Florina Raicu
    • 3
  • Radu Cojocaru
    • 4
  • Yuri Roschin
    • 5
  • Cristiana Glavce
    • 3
  • Valentin Dergachev
    • 6
  • Maria Spiridonova
    • 7
  • Horst D. Schmidt
    • 8
  • Elisabeth Weiss
    • 2
  1. 1.National Center of Reproductive Health and Medical GeneticsKishinevMoldova
  2. 2.BiocentreLudwigs-Maximilian University MunichPlanegg-MartinsriedGermany
  3. 3.Anthropological Research Centre “Francisc Rainer”Romanian AcademyBucharestRomania
  4. 4.National Scientific and Practical Centre for Preventive Medicine, Ministry of HealthKishinevMoldova
  5. 5.Medical Diagnostical Centre “Modus Vivendi”KishinevMoldova
  6. 6.Institute of Archaeology and EthnographyAcademy of Sciences of MoldovaKishinevMoldova
  7. 7.Research Institute of Medical GeneticsRussian Academy of Medical SciencesTomskRussia
  8. 8.Department of AnthropologyUniversity of UlmUlmGermany

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