Comment to: Chemical components separation with botulinum toxin A: a novel technique to improve primary fascial closure rates of the open abdomen by Zielinski et al.
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To the Editor
We read with great interest the article by Dr. Zielinski et al. . The authors presented a retrospective review of their experience with botulinum toxin A (BTA) (Botox®, Allergan, Inc. Irvine, CA 92612) application into the lateral abdominal wall musculature of open abdomen (OA) patients, in order to describe the BTA injection technique and to determine its effects on the abdominal wall after OA, which is named by the authors “chemical components separation technique.” A total of 18 patients were included. Indications for OA management included bowel viability (39 %), shock (33 %), feculent contamination (17 %), and loss of abdominal domain (6 %). A median of 3 serial abdominal explorations (1–8) after the initial OA management was required. Temporary abdominal closures with negative pressure dressings were applied. A primary fascial closure rate of 83 %, partial fascial closure rate of 6 %, and planned ventral hernia rate of 11 % are reported. The authors reported a BTA ...
- Zielinski MD, Goussous N, Schiller HJ, Jenkins D (2012) Chemical components separation with Botulinum toxin A: a novel technique to improve primary fascial closure rates of the open abdomen. Hernia. doi:10.1007/s10029-012-0995-1
- Manual of Botulinum Toxin Therapy (2009) In: Truong D, Dressler D, Hallett M (eds) Chapter 3. Pharmacology of botulinum toxin drugs. Cambridge University Press, Cambridge
- Ibarra-Hurtado, TR, Nuño-Guzmán, CM, Echeagaray-Herrera, JE, Robles-Vélez, E, González-Jaime, JJ (2009) Use of botulinum toxin type A before abdominal wall reconstruction. World J Surg 33: pp. 2553-2556 CrossRef
- Zarzaur, BL, DiCocco, JM, Shahan, CP, Emmett, K, Magnotti, LJ, Croce, MA, Hathaway, DK, Fabian, TC (2011) Quality of life after abdominal wall reconstruction following open abdomen. J Trauma 70: pp. 285-291 CrossRef
- Comment to: Chemical components separation with botulinum toxin A: a novel technique to improve primary fascial closure rates of the open abdomen by Zielinski et al.
Volume 17, Issue 1 , pp 109-110
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- 1. Department of General Surgery, Antiguo Hospital Civil de Guadalajara “Fray Antonio Alcalde”, Calle Hospital 278, Col. El Retiro, 44280, Guadalajara, Jalisco, Mexico
- 2. Pólvora 495, Interior 41. Col. Lagos del Country, 45177, Zapopan, Jalisco, Mexico