, Volume 17, Issue 1, pp 109-110
Date: 16 Nov 2012

Comment to: Chemical components separation with botulinum toxin A: a novel technique to improve primary fascial closure rates of the open abdomen by Zielinski et al.

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access
This is an excerpt from the content

To the Editor

We read with great interest the article by Dr. Zielinski et al. [1]. The authors presented a retrospective review of their experience with botulinum toxin A (BTA) (Botox®, Allergan, Inc. Irvine, CA 92612) application into the lateral abdominal wall musculature of open abdomen (OA) patients, in order to describe the BTA injection technique and to determine its effects on the abdominal wall after OA, which is named by the authors “chemical components separation technique.” A total of 18 patients were included. Indications for OA management included bowel viability (39 %), shock (33 %), feculent contamination (17 %), and loss of abdominal domain (6 %). A median of 3 serial abdominal explorations (1–8) after the initial OA management was required. Temporary abdominal closures with negative pressure dressings were applied. A primary fascial closure rate of 83 %, partial fascial closure rate of 6 %, and planned ventral hernia rate of 11 % are reported. The authors reported a BTA ...

This comment refers to the article available at: http://dx.doi.org/10.1007/s10029-012-0995-1.