Brain Tumor Pathology

, Volume 29, Issue 1, pp 47–53

Lymphomatosis cerebri: clinical characteristics, neuroimaging, and pathological findings

  • Ryuhei Kitai
  • Norichika Hashimoto
  • Kouji Yamate
  • Masamichi Ikawa
  • Makoto Yoneda
  • Tsuyoshi Nakajima
  • Hidetaka Arishima
  • Hiroaki Takeuchi
  • Kazufumi Sato
  • Ken-Ichiro Kikuta
Case Report

DOI: 10.1007/s10014-011-0064-y

Cite this article as:
Kitai, R., Hashimoto, N., Yamate, K. et al. Brain Tumor Pathol (2012) 29: 47. doi:10.1007/s10014-011-0064-y

Abstract

Lymphomatosis cerebri is a rare variant of primary central nervous system lymphoma. We present a case involving a 56-year-old immunocompetent woman who complained of rapid deterioration of her higher brain function over a 4-month period. Magnetic resonance imaging showed extensive white-matter lesions. During brain biopsy, a diffusely infiltrating lymphoma with distinctive immunohistochemical features was detected. Awareness of this unique presentation and early tissue diagnosis provide the best hope for instituting appropriate treatments.

Keywords

PCNSLLymphomatosis cerebriInfiltration

Copyright information

© The Japan Society of Brain Tumor Pathology 2011

Authors and Affiliations

  • Ryuhei Kitai
    • 1
  • Norichika Hashimoto
    • 1
  • Kouji Yamate
    • 2
  • Masamichi Ikawa
    • 2
  • Makoto Yoneda
    • 2
  • Tsuyoshi Nakajima
    • 3
  • Hidetaka Arishima
    • 1
  • Hiroaki Takeuchi
    • 1
  • Kazufumi Sato
    • 1
  • Ken-Ichiro Kikuta
    • 1
  1. 1.Department of Neurosurgery, Faculty of Medical SciencesUniversity of FukuiFukuiJapan
  2. 2.Department of Neurology, Faculty of Medical SciencesUniversity of FukuiFukuiJapan
  3. 3.Department of NeurosurgeryFukui Social Insurance HospitalFukuiJapan