Brain Tumor Pathology

, Volume 29, Issue 1, pp 47–53

Lymphomatosis cerebri: clinical characteristics, neuroimaging, and pathological findings

Authors

    • Department of Neurosurgery, Faculty of Medical SciencesUniversity of Fukui
  • Norichika Hashimoto
    • Department of Neurosurgery, Faculty of Medical SciencesUniversity of Fukui
  • Kouji Yamate
    • Department of Neurology, Faculty of Medical SciencesUniversity of Fukui
  • Masamichi Ikawa
    • Department of Neurology, Faculty of Medical SciencesUniversity of Fukui
  • Makoto Yoneda
    • Department of Neurology, Faculty of Medical SciencesUniversity of Fukui
  • Tsuyoshi Nakajima
    • Department of NeurosurgeryFukui Social Insurance Hospital
  • Hidetaka Arishima
    • Department of Neurosurgery, Faculty of Medical SciencesUniversity of Fukui
  • Hiroaki Takeuchi
    • Department of Neurosurgery, Faculty of Medical SciencesUniversity of Fukui
  • Kazufumi Sato
    • Department of Neurosurgery, Faculty of Medical SciencesUniversity of Fukui
  • Ken-Ichiro Kikuta
    • Department of Neurosurgery, Faculty of Medical SciencesUniversity of Fukui
Case Report

DOI: 10.1007/s10014-011-0064-y

Cite this article as:
Kitai, R., Hashimoto, N., Yamate, K. et al. Brain Tumor Pathol (2012) 29: 47. doi:10.1007/s10014-011-0064-y

Abstract

Lymphomatosis cerebri is a rare variant of primary central nervous system lymphoma. We present a case involving a 56-year-old immunocompetent woman who complained of rapid deterioration of her higher brain function over a 4-month period. Magnetic resonance imaging showed extensive white-matter lesions. During brain biopsy, a diffusely infiltrating lymphoma with distinctive immunohistochemical features was detected. Awareness of this unique presentation and early tissue diagnosis provide the best hope for instituting appropriate treatments.

Keywords

PCNSL Lymphomatosis cerebri Infiltration

Copyright information

© The Japan Society of Brain Tumor Pathology 2011