Brain Tumor Pathology

, Volume 24, Issue 1, pp 19–23

A rare case of extraventricular neurocytoma

Authors

    • Department of NeurosurgeryYamagata University, School of Medicine
  • Masahiro Akasaka
    • Department of NeurosurgeryYamagata University, School of Medicine
  • Hideo Kuchiki
    • Department of NeurosurgeryYamagata University, School of Medicine
  • Makoto Saino
    • Department of NeurosurgeryYamagata University, School of Medicine
  • Wataru Mori
    • Department of NeurosurgeryYamagata University, School of Medicine
  • Shinya Sato
    • Department of NeurosurgeryYamagata University, School of Medicine
  • Yoichi Nakazato
    • Department of PathologyGunma University Graduate School of Medicine
  • Takamasa Kayama
    • Department of NeurosurgeryYamagata University, School of Medicine
CASE REPORT

DOI: 10.1007/s10014-006-0210-0

Cite this article as:
Sakurada, K., Akasaka, M., Kuchiki, H. et al. Brain Tumor Pathol (2007) 24: 19. doi:10.1007/s10014-006-0210-0

Abstract

We report an unusual case of extraventricular (cerebral) neurocytoma with a long, 25-year history, and which appeared to transform to neuroblastoma. In 1978, an 18-year-old woman was treated for right frontal oligodendroglioma. Eighteen years later (in 1996), recurrence of tumor in the fourth ventricle was noted and was treated with gamma-knife radiotherapy. The tumor shrunk transiently, but 7 years later (in 2004), MRI study demonstrated a second recurrence and ventricular dissemination. Partial removal was performed, and histological examination revealed that tumor cells had round or oval nuclei with halos. Frequent mitoses and vascular proliferation were observed. The MIB-1 LI was 80%. Despite postoperative whole-brain radiotherapy to a total dose of 30 Gy, the tumor progressed, and she died at 4 months after the second surgery.

Key words

ExtraventricularNeurocytomaNeuroblastoma

Copyright information

© The Japan Society of Brain Tumor Pathology 2007