Journal of Solid State Electrochemistry

, Volume 16, Issue 9, pp 2907–2911

Efficient electrocatalytic oxidation and selective determination of isoniazid by Fe(tmphen)32+-exchanged Nafion®-modified electrode

Original Paper

DOI: 10.1007/s10008-012-1724-5

Cite this article as:
Azad, U.P. & Ganesan, V. J Solid State Electrochem (2012) 16: 2907. doi:10.1007/s10008-012-1724-5

Abstract

Cyclic voltammetry and electrochemical impedance studies of Fe(tmphen)32+ (where tmphen = 3,4,7,8-tetramethyl-1,10-phenanthroline)-immobilized Nafion®-modified glassy carbon electrode (GC/Nf/Fe(tmphen)32+) are carried out in 0.1 M Na2SO4 solution. Nafion–Fe(tmphen)32+ complex exhibits efficient electrocatalytic oxidation of isoniazid. The linear double reciprocal plot of current and concentration of isoniazid shows a Michaelis–Menten-type catalytic process. The catalytic oxidation currents are proportional to the concentration of isoniazid and show a wide linear calibration range for the quantitative determination of isoniazid. Detection limit and sensitivity are found to be 13 μM and 2.5 μA mM−1, respectively.

Keywords

Nafion®ElectrocatalysisIsoniazid oxidationFe(tmphen)32+

Supplementary material

10008_2012_1724_MOESM1_ESM.pdf (16 kb)
ESM 1(PDF 16 kb)

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  1. 1.Department of Chemistry, Faculty of ScienceBanaras Hindu UniversityVaranasiIndia