Original Paper

Journal of Solid State Electrochemistry

, Volume 14, Issue 11, pp 2095-2105

First online:

Experimental and theoretical investigations of adsorption of fexofenadine at mild steel/hydrochloric acid interface as corrosion inhibitor

  • Ishtiaque AhamadAffiliated withDepartment of Applied Chemistry, Institute of Technology, Banaras Hindu University
  • , Rajendra PrasadAffiliated withDepartment of Chemistry, Faculty of Science, Banaras Hindu University
  • , Mumtaz Ahmad QuraishiAffiliated withDepartment of Applied Chemistry, Institute of Technology, Banaras Hindu University Email author 

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Abstract

The present study examines the effect of fexofenadine, an antihistamine drug, on corrosion inhibition of mild steel in molar hydrochloric acid solution using different techniques under the influence of various experimental conditions. Results revealed that fexofenadine is an effective inhibitor and percent inhibition efficiency increased with its concentration; reaching a maximum value of 97% at a concentration of 3.0 × 10−4 M. Fourier-transform infrared spectroscopy (FTIR) observations of steel surface confirmed the protective role of the studied drug. Polarization studies showed that fexofenadine is a mixed-type inhibitor. The adsorption of the inhibitor on mild steel surface obeyed the Langmuir adsorption isotherm with free energy of adsorption (∆G°ads) of −40 kJ mol−1. Energy gaps for the interactions between mild steel surface and fexofenadine molecule were found to be close to each other showing that fexofenadine has the capacity to behave as both electron donor and electron acceptor. The results obtained from the different corrosion evaluation techniques are in good agreement.

Keywords

Corrosion inhibition Mild steel Drug Electrochemical measurement Adsorption Quantum chemical calculations