, Volume 18, Issue 2, pp 607-609,
Open Access This content is freely available online to anyone, anywhere at any time.
Date: 11 May 2011

An information-carrying and knowledge-producing molecular machine. A Monte-Carlo simulation


The concept called Knowledge is a measure of the quality of genetically transferred information. Its usefulness is demonstrated quantitatively in a Monte-Carlo simulation on critical steps in a origin of life model. The model describes the origin of a bio-like genetic apparatus by a long sequence of physical-chemical steps: it starts with the presence of a self-replicating oligomer and a specifically structured environment in time and space that allow for the formation of aggregates such as assembler-hairpins-devices and, at a later stage, an assembler-hairpins-enzyme device—a first translation machine.