European Child & Adolescent Psychiatry

, Volume 18, Issue 9, pp 583–585

Niemann–Pick disease type C1 presenting with psychosis in an adolescent male

  • Sabine Sandu
  • Sabine Jackowski-Dohrmann
  • Axel Ladner
  • Michael Haberhausen
  • Christian Bachmann
Case Report

DOI: 10.1007/s00787-009-0010-2

Cite this article as:
Sandu, S., Jackowski-Dohrmann, S., Ladner, A. et al. Eur Child Adolesc Psychiatry (2009) 18: 583. doi:10.1007/s00787-009-0010-2

Abstract

Niemann–Pick disease, a neurovisceral lysosomal lipid storage disorder, is a rare disorder that is unknown to many clinicians. The disease, that often has its onset during childhood or adolescence, shows a polymorphic clinical picture, including psychiatric symptoms. Because of its infrequence, Niemann–Pick disease is diagnosed with an average delay of 6 years. This report presents a case of an adolescent male whose symptoms had led to various hospitalisations and psychiatric diagnoses. When he presented with psychotic symptoms in our department, thorough diagnosis revealed Niemann–Pick disease type C1 as the underlying disease.

Keywords

Adolescence Niemann–Pick disease Organic psychosis Sphingomyelin lipidosis 

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Sabine Sandu
    • 1
  • Sabine Jackowski-Dohrmann
    • 1
  • Axel Ladner
    • 1
  • Michael Haberhausen
    • 1
  • Christian Bachmann
    • 1
    • 2
  1. 1.University Hospital Giessen and MarburgMarburgGermany
  2. 2.Charité, Universitätsmedizin BerlinBerlinGermany

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