European Child & Adolescent Psychiatry

, Volume 15, Supplement 1, pp i63–i71

Validity of the health-related quality of life assessment in the ADORE study: Parent Report Form of the CHIP-Child Edition

  • Anne W. Riley
  • David Coghill
  • Christopher B. Forrest
  • Maria J. Lorenzo
  • Stephen J. Ralston**
  • Georg Spiel
  • ADORE Study Group*

DOI: 10.1007/s00787-006-1009-6

Cite this article as:
Riley, A.W., Coghill, D., Forrest, C.B. et al. Eur Child Adolesc Psychiatry (2006) 15(Suppl 1): i63. doi:10.1007/s00787-006-1009-6



To examine the cross-sectional reliability and validity of the Parent Report Form of the Child Health and Illness Profile-Child Edition (CHIP-CE), a generic measure of health-related quality of life (HRQoL), in children with ADHD in the pan-European ADHD Observational Research in Europe (ADORE) study.


Parents of children with ADHD (aged 6–18 years) in 10 European countries completed the CHIP-CE at the baseline visit (n=1,477; data missing for one patient). Analyses included determination of internal consistency reliability, ceiling and floor effects, factor analysis, and Pearson's correlations between CHIP-CE and other scales used to measure ADHD severity, problems and family strain.


Internal consistency reliability was good-to-excellent (Chronbach's α>0.70) for all CHIP-CE domains and subdomains, and almost no ceiling and floor effects were observed. Factor analysis of the subdomains yielded a 12-factor solution. The domainlevel factor analysis identified six factors, the four domains of Satisfaction, Comfort, Resilience and Risk Avoidance. The two subdomains of Achievement domain, Peer Relations and Academic Performance, were separate factors in this sample. There were moderate-to-high correlations between the CHIP-CE scales and measures of ADHD and family factors. The HRQoL of children in ADORE was dramatically lower than that of community youth,with mean CHIP-CE scores almost 2 standard deviations below community norms.


The validity and reliability of CHIP-CE to measure HRQoL in children with ADHD across Europe was confirmed.

Key words

ADHDchildrenEuropefactor structurehealth-related quality of life



Attention-Deficit/Hyperactivity Disorder


ADHD Rating Scale-IV


Attention-Deficit/Hyperactivity Disorder Observational Research in Europe


Clinical Global Impression-Severity


Child Health and Illness Profile – Child Edition


Parent Report Form


Family Strain Index


Health-Related Quality of Life


Strengths and Difficulties Questionnaire

Copyright information

© Steinkopff Verlag 2006

Authors and Affiliations

  • Anne W. Riley
    • 1
  • David Coghill
    • 2
  • Christopher B. Forrest
    • 1
  • Maria J. Lorenzo
    • 3
  • Stephen J. Ralston**
  • Georg Spiel
    • 4
  • ADORE Study Group*
  1. 1.Johns Hopkins Bloomberg School of Public Health, 692 Hampton HouseBaltimore, MD 21205USA
  2. 2.Section of Psychiatry Division of Pathology and NeuroscienceUniversity of DundeeDundeeScotland, UK
  3. 3.Eli Lilly and Company, Lilly Research CentreWindlesham, SurreyUK
  4. 4.Landeskrankenhaus Klagenfurt, Dept. of Child and Adolescent NeuropsychiatryKlagenfurtAustria