Article

European Child & Adolescent Psychiatry

, Volume 15, Issue 1, pp i63-i71

Validity of the health-related quality of life assessment in the ADORE study: Parent Report Form of the CHIP-Child Edition

  • Anne W. RileyAffiliated withJohns Hopkins Bloomberg School of Public Health, 692 Hampton House Email author 
  • , David CoghillAffiliated withSection of Psychiatry Division of Pathology and Neuroscience, University of Dundee
  • , Christopher B. ForrestAffiliated withJohns Hopkins Bloomberg School of Public Health, 692 Hampton House
  • , Maria J. LorenzoAffiliated withEli Lilly and Company, Lilly Research Centre
  • , Stephen J. Ralston**
  • , Georg SpielAffiliated withLandeskrankenhaus Klagenfurt, Dept. of Child and Adolescent Neuropsychiatry
  • , ADORE Study Group*

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Abstract

Objectives

To examine the cross-sectional reliability and validity of the Parent Report Form of the Child Health and Illness Profile-Child Edition (CHIP-CE), a generic measure of health-related quality of life (HRQoL), in children with ADHD in the pan-European ADHD Observational Research in Europe (ADORE) study.

Methods

Parents of children with ADHD (aged 6–18 years) in 10 European countries completed the CHIP-CE at the baseline visit (n=1,477; data missing for one patient). Analyses included determination of internal consistency reliability, ceiling and floor effects, factor analysis, and Pearson's correlations between CHIP-CE and other scales used to measure ADHD severity, problems and family strain.

Results

Internal consistency reliability was good-to-excellent (Chronbach's α>0.70) for all CHIP-CE domains and subdomains, and almost no ceiling and floor effects were observed. Factor analysis of the subdomains yielded a 12-factor solution. The domainlevel factor analysis identified six factors, the four domains of Satisfaction, Comfort, Resilience and Risk Avoidance. The two subdomains of Achievement domain, Peer Relations and Academic Performance, were separate factors in this sample. There were moderate-to-high correlations between the CHIP-CE scales and measures of ADHD and family factors. The HRQoL of children in ADORE was dramatically lower than that of community youth,with mean CHIP-CE scores almost 2 standard deviations below community norms.

Conclusions

The validity and reliability of CHIP-CE to measure HRQoL in children with ADHD across Europe was confirmed.

Key words

ADHD children Europe factor structure health-related quality of life