Article

European Child & Adolescent Psychiatry

, Volume 15, Supplement 1, pp i38-i45

First online:

Factors related to Health-Related Quality of Life (HRQoL) among children with ADHD in Europe at entry into treatment

  • Anne W. RileyAffiliated withJohns Hopkins Bloomberg School of Public Health, 692 Hampton House Email author 
  • , Georg SpielAffiliated withLandeskrankenhaus Klagenfurt, Dept. of Child and Adolescent Neuropsychiatry
  • , David CoghillAffiliated withSection of Psychiatry, Division of Pathology and Neuroscience, University of Dundee
  • , Manfred DöpfnerAffiliated withDept. of Child and Adolescent Psychiatry, University of Cologne
  • , Bruno FalissardAffiliated withINSERM U669, Université Paris-Sud
  • , Maria J. LorenzoAffiliated withEli Lilly and Company, Lilly Research Centre
  • , Ulrich PreussAffiliated withDept. of Child and Adolescent Psychiatry, University of Bern
  • , Stephen J Ralston**
  • , ADORE Study Group*

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Abstract

Objective

To describe the associations between a range of baseline factors (demographic, family and clinical) and parent-reported health-related quality of life (HRQoL) of children with ADHD taking part in the ADORE study.

Methods

HRQoL was rated using the Parent Report Form of the Child Health and Illness Profile-Child Edition (CHIP-CE). Forward-stepwise linear regression models were used to investigate associations with 26 independent variables. Separate models were fitted for each of the five CHIP-CE domains (Satisfaction, Comfort, Resilience, Risk Avoidance and Achievement) and two subdomains of Achievement (Academic Performance and Peer Relations).

Results

CHIP-CE domain mean scores were lower than community norms, especially for Risk Avoidance and Achievement, indicating a low level of HRQoL. Clinical factors significantly associated with a poorer HRQoL included ADHD symptoms (inattention, hyperactivity-impulsivity), conduct problems, peer relationship problems, having asthma, multiple other somatic symptoms and co-ordination problems. Family factors, such as having a parent with a health or mental health problem possibly caused by the child's illness, child not living with both parents and maternal smoking during pregnancy were also associated with a worse HRQoL in some CHIP-CE domains/subdomains.

Conclusions

Numerous factors independently impact on the HRQoL of children with ADHD.

Key words

ADHD children Europe health-related quality life