Amino Acids

, Volume 32, Issue 2, pp 291–293

Methylglyoxal-derived β-carbolines formed from tryptophan and its derivates in the Maillard reaction

  • I. Nemet
  • L. Varga-Defterdarović
Short Communication

DOI: 10.1007/s00726-006-0337-7

Cite this article as:
Nemet, I. & Varga-Defterdarović, L. Amino Acids (2007) 32: 291. doi:10.1007/s00726-006-0337-7


Reaction of tryptophan, tryptophan methyl ester and tryptamine with methylglyoxal (a physiological α-oxoaldehyde), which resulted in β-carboline formation, showed that this type of nonenzymatic (Maillard) reaction could spontaneously occur in living organisms or during commercial or domestic food processing and storage.

Keywords: Methylglyoxal – Tryptophan – Tryptamine – β-Carboline – Maillard reaction

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • I. Nemet
    • 1
  • L. Varga-Defterdarović
    • 1
  1. 1.Division of Organic Chemistry and BiochemistryRuđjer Bošković InstituteZagrebCroatia