, Volume 139, Issue 12, pp 1537-1544,
Open Access This content is freely available online to anyone, anywhere at any time.
Date: 09 Jul 2008

Genomics of selected human odorant receptors

Abstract

Single nucleotide polymorphisms (SNPs) in odorant receptor genes may influence the protein sequence and consequently also the function of the receptors. An analysis of the HapMap data for human OR3A1 was performed and provided evidence that genetic differences subject to ancestry and gender can be recognized. A genomic comparison of individuals shows the diversity of odorant receptor genes and therefore potentially the variety of the sense of smell. At this time, two complete human genomes are available in public domain, which we used for this purpose.

Correspondence: Anton Beyer, Institute of Theoretical Chemistry, University of Vienna, A-1090 Vienna, Austria.