Preparation of amidoalkyl naphthols by a three-component reaction catalyzed by 2,4,6-trichloro-1,3,5-triazine under solvent-free conditions
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- Zhang, P. & Zhang, ZH. Monatsh Chem (2009) 140: 199. doi:10.1007/s00706-008-0059-5
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An efficient one-pot synthesis of amidoalkyl naphthols is described. This involves the three-component reaction of 2-naphthol, aromatic aldehydes and amide or urea in the presence of a catalytic amount of 2,4,6-trichloro-1,3,5-triazine (TCT, cyanuric chloride) under solvent-free conditions.