Monatshefte für Chemie - Chemical Monthly

, Volume 139, Issue 2, pp 133–136

Efficient Synthesis of Highly Functionalized Thiazolidine-4-ones Under Solvent-Free Conditions


DOI: 10.1007/s00706-007-0751-x

Cite this article as:
Yavari, I., Hosseini, N. & Moradi, L. Monatsh Chem (2008) 139: 133. doi:10.1007/s00706-007-0751-x


4-Phenylthiosemicarbazide reacts smoothly with dimethyl acetylenedicarboxylate in the presence of aldehydes or ketones under solvent free conditions to produce highly functionalized thiazolidine-4-ones.

Keywords. Thiazolidine-4-one; 4-Phenylthiosemicarbazide; Heterocycle synthesis; Solvent-free synthesis.

Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  1. 1.Chemistry DepartmentTarbiat Modares UniversityTehranIran