, Volume 139, Issue 2, pp 133-136

Efficient Synthesis of Highly Functionalized Thiazolidine-4-ones Under Solvent-Free Conditions

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4-Phenylthiosemicarbazide reacts smoothly with dimethyl acetylenedicarboxylate in the presence of aldehydes or ketones under solvent free conditions to produce highly functionalized thiazolidine-4-ones.