, Volume 159, Issue 10, pp 2745-2749
Date: 07 Jun 2014

Low infectivity of a novel avian-origin H7N9 influenza virus in pigs

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access


We studied the pathogenesis and transmissibility of a novel avian-origin H7N9 influenza virus in pigs. When pigs were infected with H7N9 influenza virus, they did not show any clear clinical signs (such as sneezing, fever and loss of body weight), and they shed viruses through their noses for 2 days after infection. No transmission occurred between infected and naïve pigs. Pigs suffered from mild pneumonia, which was accompanied by the induction of inflammatory cytokines and chemokines such as IL-8 and CCL1. Taken together, our results suggest that pigs may not play an active role in transmitting H7N9 influenza virus to mammals.

J. Yum and E. H. Park contributed to this work.