The complete genome sequence and molecular analysis of human hepatitis E virus genotype IV identified from a Korean patient
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- Yun, H., Kim, J.S., Lee, H.J. et al. Arch Virol (2010) 155: 1003. doi:10.1007/s00705-010-0661-9
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Hepatitis E virus (HEV) was originally identified as the etiological agent of non-HAV enterically transmitted hepatitis. One HEV strain (FJ763142) was identified from an acute viral hepatitis E patient with IgM anti-HEV in Korea. The complete genome sequence consisted of 7,238 nucleotides (nt) plus a 22-nt poly(A) tail. The strain belongs to genotype IV, with 91% homology compared with AB197674, which was found in a Japanese patient who had traveled to China. This finding suggests that HEV genotype IV already circulates in Korea, and this HEV might be the first example of an indigenous strain.