Archives of Virology

, 154:1605

Polyomaviruses KI and WU in children with respiratory tract infection

  • Andreas Mueller
  • Arne Simon
  • Julia Gillen
  • Verena Schildgen
  • Ramona Liza Tillmann
  • Karl Reiter
  • Oliver Schildgen
Original Article

DOI: 10.1007/s00705-009-0498-2

Cite this article as:
Mueller, A., Simon, A., Gillen, J. et al. Arch Virol (2009) 154: 1605. doi:10.1007/s00705-009-0498-2

Abstract

The polyomaviruses KI (KIPyV) and WU (WUPyV) have recently been discovered in specimens from patients with respiratory tract infections. To analyze the frequency and clinical impact in a cohort of pediatric patients in a German University Children’s Hospital. Nasopharyngeal aspirates or bronchoalveolar lavage specimens of 229 children with acute respiratory tract infection were screened for KIPyV and WUPyV using polymerase chain reaction-based methods. KIPyV was detected in 2 (0.9%) and WUPyV in 1 (0.4%) patients, without co-infections with other respiratory viruses but with co-detection of CMV, EBV and HHV 6 in one immunocompromised patient. Only a very small proportion (1.3%) of positive samples for KIPyV and WUPyV was documented in this study; the clinical relevance of these viruses remains unclear and requires further evaluation.

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Andreas Mueller
    • 1
  • Arne Simon
    • 1
  • Julia Gillen
    • 1
  • Verena Schildgen
    • 2
  • Ramona Liza Tillmann
    • 2
  • Karl Reiter
    • 3
  • Oliver Schildgen
    • 2
  1. 1.Department of PediatricsUniversity of BonnBonnGermany
  2. 2.Institute of VirologyUniversity of BonnBonnGermany
  3. 3.Department of PediatricsUniversity of MunichMunichGermany