Archives of Virology

, 153:1049

Genetic characterization of H1N1, H1N2 and H3N2 swine influenza virus in Thailand

  • Salin Chutinimitkul
  • Nattakarn Thippamom
  • Sudarat Damrongwatanapokin
  • Sunchai Payungporn
  • Roongroje Thanawongnuwech
  • Alongkorn Amonsin
  • Pitirat Boonsuk
  • Donruethai Sreta
  • Napawan Bunpong
  • Rachod Tantilertcharoen
  • Pornchai Chamnanpood
  • Sujira Parchariyanon
  • Apiradee Theamboonlers
  • Yong Poovorawan
Original Article

DOI: 10.1007/s00705-008-0097-7

Cite this article as:
Chutinimitkul, S., Thippamom, N., Damrongwatanapokin, S. et al. Arch Virol (2008) 153: 1049. doi:10.1007/s00705-008-0097-7

Abstract

Swine have been known to be a suitable host for influenza A virus. In Thailand, phylogenetic analysis on swine influenza virus (SIV) has as yet not been attempted. The present report presents molecular and phylogenetic analysis performed on SIV in Thailand. In this study, 12 SIV isolates from the central and eastern part of Thailand were subtyped and the molecular genetics of hemagglutinin and neuraminidase were elucidated. Three subtypes, H1N1, H1N2 and H3N2, are described. Phylogenetic analysis of the SIV hemagglutinin and neuraminidase genes shows individual clusters with swine, human or avian influenza virus at various global locations. Furthermore, amino acid substitutions were detected either at the receptor binding site or the antigenic sites of the hemagglutinin gene.

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Salin Chutinimitkul
    • 1
  • Nattakarn Thippamom
    • 2
  • Sudarat Damrongwatanapokin
    • 3
  • Sunchai Payungporn
    • 1
  • Roongroje Thanawongnuwech
    • 2
  • Alongkorn Amonsin
    • 2
  • Pitirat Boonsuk
    • 1
  • Donruethai Sreta
    • 2
  • Napawan Bunpong
    • 2
  • Rachod Tantilertcharoen
    • 2
  • Pornchai Chamnanpood
    • 3
  • Sujira Parchariyanon
    • 3
  • Apiradee Theamboonlers
    • 1
  • Yong Poovorawan
    • 1
  1. 1.Center of Excellence in Clinical Virology, Department of Pediatrics, Faculty of MedicineChulalongkorn UniversityBangkokThailand
  2. 2.Faculty of Veterinary ScienceChulalongkorn UniversityBangkokThailand
  3. 3.Department of Livestock DevelopmentNational Institute of Animal HealthBangkokThailand