Archives of Virology

, Volume 153, Issue 1, pp 211–217

Genetic analysis of four porcine avian influenza viruses isolated from Shandong, China

Authors

    • Institute of Life SciencesTaishan Medical College
  • M. J. Gibbs
    • Faculty of Science, School of Botany and ZoologyAustralian National University
  • Y. Z. Zhang
    • Chinese Academy of Sciences, Institute of Zoology
  • Z. Zhang
    • Department of Basic MedicineTaishan Medical College
  • X. M. Zhao
    • Institute of Life SciencesTaishan Medical College
  • X. Jin
    • Department of Basic MedicineTaishan Medical College
    • Chinese Academy of Sciences, Institute of Zoology
  • M. F. Yang
    • Institute of Life SciencesTaishan Medical College
  • N. N. Yang
    • Institute of Life SciencesTaishan Medical College
  • Y. J. Cui
    • Institute of Life SciencesTaishan Medical College
  • L. Ji
    • School of Public HealthGuangxi Medical University
Brief Report

DOI: 10.1007/s00705-007-1083-1

Cite this article as:
Shi, W., Gibbs, M., Zhang, Y. et al. Arch Virol (2008) 153: 211. doi:10.1007/s00705-007-1083-1

Summary

A Bayesian phylogenetic analysis of eight separate gene segments indicated A/Swine/Shandong/2/2003 (H5N1), A/Swine/Shandong/na/2003 (H9N2), A/Swine/Shandong/nb/2003 (H9N2) and A/Swine/Shandong/nc/2005 (H9N2) probably represent two multiple reassortant lineages, that had not been described before, with genes coming from H5N1, H9N2 and other lineages from poultry in Asia. Amino acid motifs within the haemagglutinin sequence of A/Swine/Shandong/nb/2003 suggested it may be able to infect people, whereas the sequences of the other three isolates suggested they would not have had that capability. Our analysis emphasizes the need for a comprehensive study of the interactions between H5N1 and H9N2 viruses in Asia that includes sequencing and phylogenetic investigation.

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Copyright information

© Springer-Verlag 2007