Archives of Virology

, Volume 152, Issue 6, pp 1201–1208

Molecular phylogeny of modern coxsackievirus A16

Authors

  • D. Perera
    • Institute of Health and Community MedicineUniversiti Malaysia Sarawak
  • M. A. Yusof
    • Institute of Health and Community MedicineUniversiti Malaysia Sarawak
    • Institute for Medical Research
  • Y. Podin
    • Institute of Health and Community MedicineUniversiti Malaysia Sarawak
  • M. H. Ooi
    • Institute of Health and Community MedicineUniversiti Malaysia Sarawak
    • Sibu Hospital
  • N. T. T. Thao
    • Pasteur Institute
  • K. K. Wong
    • Faculty of MedicineUniversiti Kebangsaan Malaysia
  • A. Zaki
    • Dr. Fakeeh Hospital
  • K. B. Chua
    • National Public Health Laboratory
  • Y. A. Malik
    • Faculty of MedicineUniversiti Kebangsaan Malaysia
    • International Medical University
  • P. V. Tu
    • Pasteur Institute
  • N. T. K. Tien
    • Pasteur Institute
  • P. Puthavathana
    • Faculty of Medicine Siriraj HospitalMahidol University
  • P. C. McMinn
    • Telethon Institute for Child Health Research
  • M. J. Cardosa
    • Institute of Health and Community MedicineUniversiti Malaysia Sarawak
Brief Report

DOI: 10.1007/s00705-006-0934-5

Cite this article as:
Perera, D., Yusof, M., Podin, Y. et al. Arch Virol (2007) 152: 1201. doi:10.1007/s00705-006-0934-5

Summary.

A phylogenetic analysis of VP1 and VP4 nucleotide sequences of 52 recent CVA16 strains demonstrated two distinct CVA16 genogroups, A and B, with the prototype strain being the only member of genogroup A. CVA16 G-10, the prototype strain, showed a nucleotide difference of 27.7–30.2% and 19.9–25.2% in VP1 and VP4, respectively, in relation to other CVA16 strains, which formed two separate lineages in genogroup B with nucleotide variation of less than 13.4% and less than 16.3% in VP1 and VP4, respectively. Lineage 1 strains circulating before 2000 were later displaced by lineage 2 strains.

Copyright information

© Springer-Verlag 2007