, Volume 152, Issue 3, pp 457-461
Date: 27 Nov 2006

Binding activity of norovirus and sapovirus to histo-blood group antigens

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Noroviruses (NoVs) and sapoviruses (SaVs) are causative agents of human gastroenteritis. There is increasing evidence that certain human NoV strains bind to histo-blood group antigens (HBGAs). We found that several NoV virus-like particles (VLPs) showed binding activity to HBGAs, while neither SaV genogroup I (GI) VLP nor SaV GV VLP showed such activity.