Archives of Virology

, Volume 147, Issue 11, pp 2197–2205

Genetic and antigenic typing of rabies virus in Chile

Brief Report
  • V. Yung
  • M. Favi
  • J. Fernández

DOI: 10.1007/s00705-002-0894-3

Cite this article as:
Yung, V., Favi, M. & Fernández, J. Arch Virol (2002) 147: 2197. doi:10.1007/s00705-002-0894-3

Summary.

 Forty-one isolates of rabies virus from insectivorous bats and one from a domestic cat in Chile, were characterized using eight anti-nucleoprotein monoclonal antibodies (N-Mabs) and by nucleotide sequence analysis. Thirty-two isolates were identified as antigenic variant 4 associated with Tadarida brasiliensis bats, twenty-eight were genetically associated with variant Tadarida brasiliensis and four with Lasiurus sp. bats. One isolate was identified as antigenic variant 3 associated with Desmodus rotundus bats, and by genetic analysis was identified as variant Myotis sp. bat. Eight isolates were unrelated to any antigenic variant, and they were identified as a genetic variant associated with Histiotus sp. bats. These antigenic and genetic characterizations may establish epidemiological links between rabies cases and increase the understanding of rabies epidemiology in this country.

Copyright information

© Springer-Verlag/Wien 2002

Authors and Affiliations

  • V. Yung
    • 1
  • M. Favi
    • 1
  • J. Fernández
    • 2
  1. 1.Laboratorio de Diagnóstico de Rabia, Instituto de Salud Pública de Chile, Santiago, ChileCL
  2. 2.Unidad de Desarrollo Tecnológico, Instituto de Salud Pública de Chile, Santiago, ChileCL