Journal of Neural Transmission

, Volume 120, Issue 10, pp 1441–1445

A preliminary method development study to identify potential stroke biomarkers in plasma using multiple chromatographies with nanoLC-ESIMS detection


  • Phanichand Kodali
    • Department of ChemistryUniversity of Cincinnati
  • Julio A. Landero-Figueroa
    • Department of ChemistryUniversity of Cincinnati
    • Department of ChemistryUniversity of Cincinnati
  • Opeolu Adeoye
    • Department of Emergency MedicineUniversity of Cincinnati
Neurology and Preclinical Neurological Studies - Short communication

DOI: 10.1007/s00702-013-1018-9

Cite this article as:
Kodali, P., Landero-Figueroa, J.A., Caruso, J. et al. J Neural Transm (2013) 120: 1441. doi:10.1007/s00702-013-1018-9


Stroke is the leading cause of disability in the USA. Rapid, reliable diagnosis via a point-of-care blood test may facilitate earlier treatment to reduce disability. We have recently reported detailed methods of chromatographic separations of plasma samples coupled with nanoESI-ion trap a list of proteins which are viable candidates for further investigation as stroke biomarkers.


Blood plasmaBiomarkersHPLCStroke

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© Springer-Verlag Wien 2013