Journal of Neural Transmission

, Volume 120, Issue 10, pp 1441–1445

A preliminary method development study to identify potential stroke biomarkers in plasma using multiple chromatographies with nanoLC-ESIMS detection

  • Phanichand Kodali
  • Julio A. Landero-Figueroa
  • Joseph Caruso
  • Opeolu Adeoye
Neurology and Preclinical Neurological Studies - Short communication

DOI: 10.1007/s00702-013-1018-9

Cite this article as:
Kodali, P., Landero-Figueroa, J.A., Caruso, J. et al. J Neural Transm (2013) 120: 1441. doi:10.1007/s00702-013-1018-9
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Abstract

Stroke is the leading cause of disability in the USA. Rapid, reliable diagnosis via a point-of-care blood test may facilitate earlier treatment to reduce disability. We have recently reported detailed methods of chromatographic separations of plasma samples coupled with nanoESI-ion trap a list of proteins which are viable candidates for further investigation as stroke biomarkers.

Keywords

Blood plasmaBiomarkersHPLCStroke

Copyright information

© Springer-Verlag Wien 2013

Authors and Affiliations

  • Phanichand Kodali
    • 1
  • Julio A. Landero-Figueroa
    • 1
  • Joseph Caruso
    • 1
  • Opeolu Adeoye
    • 2
  1. 1.Department of ChemistryUniversity of CincinnatiCincinnatiUSA
  2. 2.Department of Emergency MedicineUniversity of CincinnatiCincinnatiUSA