Journal of Neural Transmission

, Volume 120, Issue 8, pp 1259–1270

CID: a valid incentive delay paradigm for children

  • Viola Kappel
  • Anne Koch
  • Robert C. Lorenz
  • Rüdiger Brühl
  • Babette Renneberg
  • Ulrike Lehmkuhl
  • Harriet Salbach-Andrae
  • Anne Beck
Psychiatry and Preclinical Psychiatric Studies - Original Article

DOI: 10.1007/s00702-012-0962-0

Cite this article as:
Kappel, V., Koch, A., Lorenz, R.C. et al. J Neural Transm (2013) 120: 1259. doi:10.1007/s00702-012-0962-0

Abstract

Despite several modifications and the wide use of the monetary incentive delay paradigm (MID; Knutson et al. in J Neurosci 21(16):RC159, 2001a) for assessing reward processing, evidence concerning its application in children is scarce. A first child-friendly MID modification has been introduced by Gotlib et al. (Arch Gen Psychiatry 67(4): 380–387, 2010); however, comparability in the results of different tasks and validity across different age groups remains unclear. We investigated the validity of a newly modified MID task for children (CID) using functional magnetic resonance imaging. The CID comprises the integration of a more age appropriate feedback phase. We focused on reward anticipation and their neural correlates. Twenty healthy young adults completed the MID and the CID. Additionally, 10 healthy children completed the CID. As expected, both paradigms elicited significant ventral and dorsal striatal activity in young adults during reward anticipation. No differential effects of the tasks on reaction times, accuracy rates or on the total amount of gain were observed. Furthermore, the CID elicited significant ventral striatal activity in healthy children. In conclusion, these findings demonstrate evidence for the validity of the CID paradigm. The CID can be recommended for the application in future studies on reward processing in children, adolescents, and in adults.

Keywords

Children Monetary incentive delay paradigm Reward anticipation Validity Ventral striatum 

Copyright information

© Springer-Verlag Wien 2013

Authors and Affiliations

  • Viola Kappel
    • 1
    • 2
  • Anne Koch
    • 1
  • Robert C. Lorenz
    • 3
    • 4
  • Rüdiger Brühl
    • 5
  • Babette Renneberg
    • 2
  • Ulrike Lehmkuhl
    • 1
  • Harriet Salbach-Andrae
    • 1
  • Anne Beck
    • 3
  1. 1.Department of Child and Adolescent Psychiatry, Psychosomatics and PsychotherapyCharité-Universitätsmedizin BerlinBerlinGermany
  2. 2.Clinical Psychology and PsychotherapyFreie Universität BerlinBerlinGermany
  3. 3.Department of Psychiatry and PsychotherapyCharité-Universitätsmedizin BerlinBerlinGermany
  4. 4.Department of PsychologyHumboldt Universität zu BerlinBerlinGermany
  5. 5.Physikalisch Technische Bundesanstalt BerlinBerlinGermany

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