Journal of Neural Transmission

, Volume 120, Issue 2, pp 339–342

Steroids in bacterial meningitis: yes

Neurology and Preclinical Neurological Studies - CONy Pro/Con debate

DOI: 10.1007/s00702-012-0938-0

Cite this article as:
Benninger, F. & Steiner, I. J Neural Transm (2013) 120: 339. doi:10.1007/s00702-012-0938-0

Abstract

Bacterial meningitis is an infectious condition associated with severe morbidity and mortality, even with rapid diagnosis and appropriate antibiotic therapy. Despite decrease in the rate of bacterial meningitis brought about by vaccination programs against Haemophilus influenzae type-B and Streptococcus pneumonia, the incidence of meningitis is still unacceptably high and acute treatment remains the mainstay of therapy. The infection is accompanied by intense inflammatory response, which may carry deleterious effects upon the tissue. This led to the possibility of adjuvant corticosteroid therapy, as an anti-inflammatory agent, in bacterial meningitis. The debate focuses on the rational and evidence supporting and refuting such an approach.

Keywords

Meningitis Steroids Treatment Bacterial 

Copyright information

© Springer-Verlag Wien 2012

Authors and Affiliations

  1. 1.Department of NeurologyRabin Medical Center, Campus BeilinsonPetach TikvaIsrael

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