Journal of Neural Transmission

, Volume 116, Issue 9, pp 1087–1092

Functional MRI in the assessment of cortical activation during gait-related imaginary tasks

  • JiunJie Wang
  • YauYau Wai
  • YiHsin Weng
  • KoonKwan Ng
  • Ying-Zu Huang
  • Leslie Ying
  • HaoLi Liu
  • ChiHong Wang
Movement Disorders - Original Article

DOI: 10.1007/s00702-009-0269-y

Cite this article as:
Wang, J., Wai, Y., Weng, Y. et al. J Neural Transm (2009) 116: 1087. doi:10.1007/s00702-009-0269-y

Abstract

Imaginary tasks can be used to investigate the neurophysiology of gait. In this study, we explored the cortical control of gait-related imagery in 21 healthy volunteers using functional magnetic resonance imaging. Imaginary tasks included gait initiation, stepping over an obstacle, and gait termination. Subjects watched a video clip that showed an actor in gait motion under an event-related design. We detected activation in the supplementary motor area during major gait-related imagery tasks, and especially during gait initiation. During gait termination and stepping over an obstacle, the amount of cortical resources allocated to the imaginary tasks included a large visuomotor network comprising the dorsal and ventral premotor areas. We conclude that our paradigm to study the cortical control of gait may help in elucidating the pathophysiology of higher-level gait disorders.

Keywords

Gait Initiation Step over Termination Supplementary motor area 

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • JiunJie Wang
    • 1
    • 2
  • YauYau Wai
    • 1
    • 2
  • YiHsin Weng
    • 3
  • KoonKwan Ng
    • 4
    • 5
  • Ying-Zu Huang
    • 3
  • Leslie Ying
    • 6
  • HaoLi Liu
    • 7
  • ChiHong Wang
    • 8
  1. 1.Department of Medical Imaging and Radiological SciencesChangGung UniversityTaoYuanTaiwan
  2. 2.Department of Diagnostic Radiology and InterventionChangGung Memorial HospitalLinKouTaiwan
  3. 3.Department of NeurologyChangGung Memorial HospitalLinKouTaiwan
  4. 4.Department of MedicineChangGung UniversityTaoYuanTaiwan
  5. 5.Department of Diagnostic RadiologyChangGung Memorial HospitalKeeLungTaiwan
  6. 6.Department of Electrical Engineering and Computer ScienceUniversity of WisconsinMilwaukeeUSA
  7. 7.Department of Electrical EngineeringChangGung UniversityTaoYuanTaiwan
  8. 8.Department of NeurologyCardinal Tien Hospital YungHo BranchYung-HoTaiwan

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