Journal of Neural Transmission

, 115:1159

Dopaminergic modulation of emotional memory in Parkinson’s disease

  • Thomas D. Hälbig
  • Ute A. Kopp
  • Franziska Wodarz
  • Joan C. Borod
  • Jean-Michel Gracies
  • Georg Ebersbach
  • Andreas Kupsch
Parkinson's Disease and Allied Conditions - Short Communication

DOI: 10.1007/s00702-008-0061-4

Cite this article as:
Hälbig, T.D., Kopp, U.A., Wodarz, F. et al. J Neural Transm (2008) 115: 1159. doi:10.1007/s00702-008-0061-4

Abstract

The aim of this study was to assess the effect of dopaminergic treatment on emotional memory in patients with Parkinson’s disease (PD). We tested memory for emotional and neutral visual stimuli in ten non-demented PD patients on and off dopaminergic medication. Patients recalled significantly more emotional items during the off- than on-medication testing session. In contrast, treatment condition did not affect memory for neutral items. These findings demonstrate that emotional memory deficits observed in PD may result from dopaminergic treatment and suggest an involvement of dopaminergic neurotransmission in emotional processing.

Keywords

Parkinson’s disease Emotional memory Basal ganglia Dopamine 

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Thomas D. Hälbig
    • 1
    • 5
  • Ute A. Kopp
    • 1
  • Franziska Wodarz
    • 1
  • Joan C. Borod
    • 2
    • 3
  • Jean-Michel Gracies
    • 2
  • Georg Ebersbach
    • 4
  • Andreas Kupsch
    • 1
  1. 1.Department of NeurologyCharité, Universitätsmedizin BerlinBerlinGermany
  2. 2.Department of NeurologyMount Sinai School of MedicineNew YorkUSA
  3. 3.Department of Psychology, Queens College and The Graduate CenterCity University of New YorkFlushingUSA
  4. 4.Department of Movement DisordersNeurologisches FachkrankenhausBeelitz-HeilstättenGermany
  5. 5.Fédération de Neurologie & Centre d’Investigation CliniqueCentre Hospitalier Universitaire Pitié-SalpêtrièreParis cedex 13France