Journal of Neural Transmission

, 114:777

Ceruloplasmin and what it might do

Authors

  • J. Healy
    • Department of BiochemistrySchool of Biochemistry and Immunology, Trinity College
  • K. Tipton
    • Department of BiochemistrySchool of Biochemistry and Immunology, Trinity College
Amine oxidase structure and function

DOI: 10.1007/s00702-007-0687-7

Cite this article as:
Healy, J. & Tipton, K. J Neural Transm (2007) 114: 777. doi:10.1007/s00702-007-0687-7

Summary

The blue coloured plasma protein ceruloplasmin binds up to 95% of circulating copper, and has several possible functions. It has been proposed to function in copper transport, oxidation of organic amines, iron(II) oxidation and the regulation of cellular iron levels, and catechols, radical scavenging and other antioxidant processes. This account will consider the relative importance of these multiple functions in terms of the physiological roles of ceruloplasmin.

Keywords: Ceruloplasmin, copper, amine oxidase, ferroxidase, iron, catechol oxidase
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© Springer-Verlag 2007