Long-term seizure outcome after stereotactic amygdalohippocampectomy
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The aim of the study was to evaluate the long-term seizure outcome and complications after stereotactic radiofrequency amygdalohippocampectomy (SAHE) performed for mesial temporal lobe epilepsy (MTLE).
The article describes the cases of 61 patients who were treated at our institution during the period 2004–2010. Mean post-operative follow-up was 5.3 years.
At the last postsurgical visit, 43 (70.5 %) patients were Engel Class I, six (9.8 %) Class II, nine (14.8 %) Class III and three (4.9 %) Class IV. The surgery was complicated by four intracranial haematomas. One of them caused acute hydrocephalus and was treated by shunting and resolved without sequelae. After SAHE, we performed open epilepsy surgery and re-thermo lesions in three and two patients, respectively (8.2 %). There were two cases of meningitis which required antibiotic treatment. In six patients psychiatric disorders developed and one of these committed suicide due to postoperative depression.
Our results provide preliminary evidence for good long-term seizure outcomes after SAHE. SAHE could be an alternative therapy for MTLE.
- Long-term seizure outcome after stereotactic amygdalohippocampectomy
Volume 156, Issue 8 , pp 1529-1537
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- Springer Vienna
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- Stereotactic neurosurgery
- Temporal lobe epilepsy
- Epilepsy surgery
- Hippocampal sclerosis
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- Author Affiliations
- 1. Department of Neurology, Na Homolce Hospital, Roentgenova 2, 150 30 5 - Motol, Prague, Czech Republic
- 3. Department of Radiology, Na Homolce Hospital, Prague, Czech Republic
- 2. Department of Psychology, Na Homolce Hospital, Prague, Czech Republic
- 6. Department of Cybernetics, Faculty of Electrical Engineering, Czech Technical University, Prague, Czech Republic
- 4. Department of Pathology, Na Homolce Hospital, Prague, Czech Republic
- 7. Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic
- 5. Department of Stereotactic and Radiation Neurosurgery, Na Homolce Hospital, Prague, Czech Republic