Acta Neurochirurgica

, Volume 154, Issue 5, pp 807–813

Vascular compression of the cochlear nerve and tinnitus: a pathophysiological investigation

  • Dirk De Ridder
  • Sven Vanneste
  • Ine Adriaensens
  • Alison Po Kee Lee
  • Paul van de Heyning
  • Aage Möller
Clinical Article

DOI: 10.1007/s00701-012-1307-3

Cite this article as:
De Ridder, D., Vanneste, S., Adriaensens, I. et al. Acta Neurochir (2012) 154: 807. doi:10.1007/s00701-012-1307-3

Abstract

Objective

Chronic microvascular compressions of the eighth nerve induce a slowing down of signal transmission in the auditory nerve, electrophysiologically characterized by IPL I-III prolongation.

Methods

The authors hypothesize this is compensated by an active slowing down of signal transmission of the contralateral input at the level of the brainstem, characterized by contralateral IPL III-V prolongation.

Results

Differences between ipsilateral and contralateral IPL I-III and IPL III-V are analyzed before and after microvascular decompression. ABR diagnostic criteria for microvascular compression are ipsilateral IPL I-III prolongation or ipsilateral peak II decrease + ipsilateral IPL I-III prolongation. With IPL I-III as diagnostic criterion, unlike preoperatively the difference between the ipsi- and contralateral IPL I-III is significant postoperatively. When using the stricter diagnostic criterion of IPL I-III + peak II, there is a preoperative significant difference between ipsi- and contralateral IPL I-III, but postoperatively the difference between the ipsi- and contralateral IPL I-III is not significant.

Conclusions

Preoperatively, there is a marginal significant difference between the ipsi- and contralateral IPL III-V, which disappears postoperatively.

Keywords

ABR BAEP Tinnitus MVC MVD operations Auditory nerve pathophysiology 

Abbreviations

ABR

Auditory brainstem response

dB HL

Decibel hearing loss

IPL

Interpeak latency

MVC

Microvascular compression

MVD

Microvascular decompression

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Dirk De Ridder
    • 1
  • Sven Vanneste
    • 1
  • Ine Adriaensens
    • 1
  • Alison Po Kee Lee
    • 1
  • Paul van de Heyning
    • 2
  • Aage Möller
    • 3
  1. 1.TRI Tinnitus Clinic, BRAI²N & Department of NeurosurgeryUniversity Hospital AntwerpEdegemBelgium
  2. 2.TRI Tinnitus Clinic, BRAI²N & Department of ENTUniversity Hospital AntwerpEdegemBelgium
  3. 3.School of Behavior and Brain SciencesUniversity of Texas at DallasRichardsonUSA

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