Acta Neurochirurgica

, 153:2067

Three cases of superficial siderosis of the central nervous system and review of the literature

Authors

    • Department of NeurosurgeryTurku University Hospital
  • Seppo Juvela
    • Department of NeurosurgeryTurku University Hospital
  • Riitta Parkkola
    • Department of RadiologyTurku University Hospital
  • Susanna Roine
    • Department of NeurologyTurku University Hospital
Review Article

DOI: 10.1007/s00701-011-1116-0

Cite this article as:
Posti, J.P., Juvela, S., Parkkola, R. et al. Acta Neurochir (2011) 153: 2067. doi:10.1007/s00701-011-1116-0

Abstract

Superficial siderosis of the central nervous system results from chronic or intermittent hemorrhage into the subarachnoid space that causes hemosiderin deposition in subpial layers of the brain and the spinal cord leading to neuronal damage. Patients present with progressive and debilitating symptoms that typically include adult-onset slowly progressive cerebellar gait ataxia and sensorineural hearing impairment. Regardless of extensive investigations, the origin of the hemorrhage is often not clear. Because of the good availability of magnetic resonance imaging, asymptomatic cases of superficial siderosis of the central nervous system are increasingly discovered. SS cases are increasingly reported in the literature. We present three new cases. The etiology, pathogenesis, clinical features, and treatment options of SS are reviewed.

Keywords

SiderosisHemosiderosisHemosiderinCentral nervous systemSubarachnoid hemorrhageSensorineural deafnessAtaxiaBrachial plexus injury

Copyright information

© Springer-Verlag 2011