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These comments are fair. I accept and think I have stated that the extended clival approach for chordomas and chondrosarcomas is much improved by endoscopy, and in experienced hands is not only far less destructive than open surgery but also more likely to result in higher tumour resection percentages. I would generally agree with this for craniopharyngiomas, although for a long time we have known that, despite radical excision, recurrence rates are high, and until we have longer-term endoscopic results, rather than nice early postopertative pictures, we must remain guarded.
Regarding functioning adenomas in the cavernous sinus, I feel there is far too little in the literature to tell (actually virtually none), as we already know that we are generally less successful at complete removal by any method outside the confines of the fossa and these patients almost always undergo some additional oncological treatment—usually some form of radiation therapy. The approaches exist, but until we have some longer-term evidence, this cynical pituitary surgeon with over 3,000 cases experience would say that the case is “not proven”—as judges say in the High Court.
Michael Powell
London, UK
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Fernandez-Miranda, J.C., Prevedello, D.M., Gardner, P. et al. Endonasal endoscopic pituitary surgery: is it a matter of fashion?. Acta Neurochir 152, 1281–1282 (2010). https://doi.org/10.1007/s00701-009-0487-y
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DOI: https://doi.org/10.1007/s00701-009-0487-y