Acta Neurochirurgica

, Volume 146, Issue 12, pp 1301–1308

Differential patterns of cognitive impairment in patients with aqueductal stenosis and normal pressure hydrocephalus


  • A. Donnet
    • Neurosurgical DepartmentCHU Timone
  • A. Schmitt
    • Neurosurgical DepartmentCHU Timone
  • H. Dufour
    • Neurosurgical DepartmentCHU Timone
  • R. Giorgi
    • LERTIM, CHU Timone
  • F. Grisoli
    • Neurosurgical DepartmentCHU Timone
Clinical Article

DOI: 10.1007/s00701-004-0384-3

Cite this article as:
Donnet, A., Schmitt, A., Dufour, H. et al. Acta Neurochir (2004) 146: 1301. doi:10.1007/s00701-004-0384-3


Methods. We report a preoperative neuropsychological evaluation for ten adult patients with aqueductal stenosis, and compare the results of this group with a normal pressure hydrocephalus group.

Findings. For executive functions, aqueductal stenosis patients failed on isolated tests and results were heterogeneous; the normal pressure hydrocephalus group was more impaired, except for tasks which required memory processing. Memory deficits in aqueductal stenosis group are qualitatively dissimilar and more homogeneous and severe, despite the younger age, than in the normal pressure hydrocephalus group.

Interpretation. These findings indicate that neuropsychological deficits of patients with aqueductal stenosis are linked with fornix damage and frontal dysfunction. In the normal pressure hydrocephalus group, deficits could be linked with a prefrontal lobe disconnection.

Keywords: Aqueductal stenosis; normal pressure hydrocephalus; memory.
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Copyright information

© Springer-Verlag/Wien 2004